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The aging brain undergoes a cascade of structural changes — subcortical volumes shrink, functional connectivity networks reorganize, and the boundar…...
Most research on cognitive aging relies on either cross-sectional comparisons — snapshots of cognition at a single time point — or pre-defined cli…...
Identifying individuals at risk of cognitive decline is only half the problem. The other half — and arguably the harder half — is determining what…...
Physical activity is widely recognized as one of the most robust modifiable protective factors against cognitive decline. But the relationship between…...
Lithium has been used for decades as a mood stabilizer in bipolar disorder, but a growing body of epidemiological evidence suggests it may also confer…...
Centenarians are statistical outliers — individuals who have survived to the extreme tail of the human lifespan. While genetics undoubtedly plays a …...
Type-2 diabetes approximately doubles the risk of Alzheimer’s disease. This association is well established epidemiologically, but the specific …...
The relationship between metabolic health and brain function is typically studied in older adults, often after cognitive decline has already begun. Bu…...
Not everyone ages the same way. While cognitive decline is common in older adults, a remarkable subset — often called “Super-Agers” or …...